I awoke one morning late last year to find a bright red bauble at the foot of my bed. It wouldn’t have looked amiss adorning a Christmas tree. But it felt ready to explode. It was my big toe, and this was my first encounter with gout.
In good company
With a history spanning more than 4,500 years, gout is among our earliest recorded diseases. Hippocrates, traditionally regarded as the father of medicine, called it “the unwalkable disease”, because it was very painful for people with gout to walk.
This moniker also reflects the fact gout has historically been associated with indulging in rich food and excessive alcohol. Scientific evidence today suggests this may have something to do with it, though the common belief drinking port specifically causes gout is unfounded.
And some stigma still clings to the condition. Often gout is seen as being self-inflicted, a mark of overindulgence. But living with gout has far-reaching implications, hampering a person’s ability to participate in everyday life.
Read more: Got gout? Here's what to eat and avoid
What is gout?
Gout is the most common form of inflammatory arthritis. It’s caused by sodium urate crystals forming in the joints. While the big toe is particularly susceptible, gout can also affect the ankles, knees, elbows, wrists and fingers.
Urate, or uric acid, is an end-product of the breakdown of biochemicals called purines, which are both components of your DNA and absorbed into the body through the foods you eat. Urate levels reflect how much is made in the liver and how much is flushed out when you go to the toilet.
If your urate levels become too high, the urate turns into crystals. When urate crystals form in the fluid cushioning a joint, the body’s defence forces see them as foreign invaders. Inflammation and debilitating pain follow.
What causes gout?
A high level of urate in the blood is the greatest risk factor for gout. But what causes high levels of urate? While we don’t know exactly, several factors certainly contribute.
Gout is also more common in males — almost 80% of people with gout are male. One reason for this is the female sex hormone oestrogen lowers urate levels, and is therefore protective against gout in pre-menopausal women.
Management and prevention
You should ice and raise the affected joint and minimise contact with it — even a light bedsheet can cause excruciating pain.
Attacks of gout can last for days or weeks. If you think you have gout, you should see your doctor.
Many people who have one gout attack will go on to have more. In one study, 70% of people who had an attack of gout went on to have another within a year.
You might also consider minimising consumption of purine-rich foods, which include meat, seafood and yeast products, like Vegemite.
But as with any diet, sticking to a low-purine diet can be challenging. Evidence for particular foods to favour or avoid for gout is weak, and overall, diet contributes very little to variation in urate levels.
With a red bauble stuck on the end of your foot, you learn to appreciate how important your big toe is for mobility.
Eventually, I managed to drop my COVID kilos, by watching portion sizes, not going back for seconds, replacing unhealthy snacks with fruit, and cutting back on alcohol.
And with that, I’m hoping my first encounter with gout might be my last. Although keeping off the kilos will require constant vigilance, the memory of that painful red bauble should be a powerful motivator.
The authors do not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and have disclosed no relevant affiliations beyond their academic appointment.
Read the full article here.
This content was originally published by The Conversation. Original publishers retain all rights. It appears here for a limited time before automated archiving.By The Conversation